On January 8, 2004, Polisetti, Dharma Rao; Kodra, Janos Tibor; Lau, Jesper; Bloch, Paw; Valcarce-Lopez, Maria Carmen; Blume, Niels; Guzel, Mustafa; Santhosh, Kalpathy Chidambareswaran; Mjalli, Adnan M. M.; Andrews, Robert Carl; Subramanian, Govindan; Ankersen, Michael; Vedso, Per; Murray, Anthony; Jeppesen, Lone published a patent.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate The title of the patent was Preparation of thiazolyl aryl ureas as activators of glucokinase. And the patent contained the following:
The title compounds [I; A1 = arylene, heteroarylene, fused cycloalkylarylene, etc.; L1 = a bond, O, S, SO, etc.; G1 = alkyl, cycloalkyl, cycloalkylalkylene, etc.; L2 = a bond, alkylene, alkenylene, etc.; L3 = CO, COCO, COCH2CO, SO2; R1 = alkyl, alkenyl, alkynyl, etc.; G2 = heteroaryl, fused heterocyclylheteroaryl, cycloalkylheteroaryl, etc.] which are activators of glucokinase and may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial (no data), were prepared and formulated. Thus, reacting 2-phenoxyaniline with 2-aminothiazole and 1,1′-carbonyldiimidazole afforded 95% the urea II. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate
The Article related to thiazolyl aryl urea preparation formulation glucokinase activator antidiabetic and other aspects.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate
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