Mertens, Chiel; Aksakal, Resat; Badi, Nezha; Du Prez, Filip E. published an article in 2021, the title of the article was Sequence-defined oligoampholytes using hydrolytically stable vinyl sulfonamides: design and UCST behavior.Related Products of 6038-19-3 And the article contains the following content:
Polyampholytes, widely investigated for their distinct properties, are typically prepared via conventional polymerization techniques. This results in an ensemble of polymer chains with variation in mol. parameters such as length, ratio of charged groups and monomer order, which could influence their behavior. Here, uniform oligoampholytes with precisely positioned neg. charged carboxylate and pos. charged ammonium side-chains were synthesized using an iterative solid-phase synthesis strategy based on thiolactone chem. The amine side-chains were initially introduced via an acrylate, resulting in an amino-functionalized β-thioester that was shown to be susceptible to transesterification and hydrolysis, even under ambient conditions. While increasing the spacer length between the β-thioester and amine functionality could slow down this undesired side-reaction, it could not be completely suppressed. On the other hand, a tertiary amine-bearing vinyl sulfonamide proved to be a viable, hydrolytically stable alternative to introduce this moiety. The resulting uniform oligoampholytes are soluble in water and show UCST-type thermo responsive behavior in 85 vol% isopropanol/water mixtures The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Related Products of 6038-19-3
The Article related to hydrolytically stable vinyl sulfonamide sequence defined oligo ampholyte, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Related Products of 6038-19-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics