Zhao, Baoli published an article in 2012, the title of the article was Pd-Catalyzed C-3 functionalization of indolizines via C-H bond cleavage.Product Details of 93476-46-1 And the article contains the following content:
New transition metal-catalyzed methods for the arylation of indolizines by the direct cleavage of C-H bonds have been developed. A wide range of aryltrifluoroborate salts react with indolizines in the presence of Pd(OAc)2 catalyst and AgOAc oxidant to give the arylated indolizines in high yields. Both electron-donating and electron-withdrawing groups perform smoothly while bromide and chlorine substituents are tolerated. In addition, the indolizines display similar reactivities in the Pd-catalyzed reaction with 3-phenylpropiolic acid to afford the corresponding C-3 alkynylated indolizines. These methods allow the direct functionalization of indolizines in one step. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Product Details of 93476-46-1
The Article related to palladium catalyzed functionalization indolizine carbon hydrogen bond cleavage, Physical Organic Chemistry: Addition, Elimination, and Substitution Reactions and other aspects.Product Details of 93476-46-1
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