On March 18, 2011, Yang, Yuzhu; Chen, Li; Zhang, Zhaoguo; Zhang, Yuhong published an article.Formula: C11H11NO2 The title of the article was Palladium-Catalyzed Oxidative C-H Bond and C=C Double Bond Cleavage: C-3 Acylation of Indolizines with α,β-Unsaturated Carboxylic Acids. And the article contained the following:
A novel palladium-catalyzed C-3 acylation of indolizines with α,β-unsaturated carboxylic acids via C-H bond and C=C double bond cleavage under oxidative conditions is described. E.g., in presence of PdCl2 and K2CrO4, acylation of indolizine I with cinnamic acid II gave 64% III. The regioselectivity is assisted by the carboxylic group, and the selection of the oxidant is crucial to the reaction. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Formula: C11H11NO2
The Article related to palladium catalyst acylation indolizine unsaturated carboxylic acid, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Formula: C11H11NO2
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