On June 15, 2011, Zhang, Yuhong; Huang, Lehao; Xie, Yongju; Niu, Tianmin published a patent.Application In Synthesis of Ethyl indolizine-1-carboxylate The title of the patent was Process for preparation of indolizine Mannich base-like compound. And the patent contained the following:
A process for preparation of indolizine Mannich base deri. is disclosed. The claimed title compound is shown in structure I (R = cyano, methoxycarbonyl, or ethoxycarbonyl; R1 = Me, Et, tert-Bu, H, or Cl; R2 = Me, H, or Cl; R3 = Me, Ph, or H). The claimed compound is prepared with N,N-dimethylaniline II and indolizine III via condensation reaction in the presence of catalyst. The catalyst is selected from CuCl, CuBr, CuI, or Cu2O. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Application In Synthesis of Ethyl indolizine-1-carboxylate
The Article related to indolizine mannich base preparation dimethylaniline indolizine condensation cuprous catalysis, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Application In Synthesis of Ethyl indolizine-1-carboxylate
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