Tanasova, Marina; Anyika, Mercy; Borhan, Babak published an article in 2015, the title of the article was Sensing Remote Chirality: Stereochemical Determination of β-, γ-, and δ-Chiral Carboxylic Acids.Name: (R)-Methyl 3-hydroxybutanoate And the article contains the following content:
Determining the absolute stereochem. of small mols. bearing remote nonfunctionalizable stereocenters is a challenging task. Presented is a solution in which appropriately substituted bis(porphyrin) tweezers are used. Complexation of a suitably derivatized β-, γ-, or δ-chiral carboxylic acid to the tweezer induces a predictable helicity of the bis(porphyrin), which is detected as a bisignate Cotton Effect (ECCD). The sign of the ECCD curve is correlated with the absolute stereochem. of the substrate based on the derived working mnemonics in a predictable manner. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Name: (R)-Methyl 3-hydroxybutanoate
The Article related to sensing remote chirality stereochem chiral carboxylic acid, chirality, circular dichroism, host-guest systems, stereochemistry, zinc, Physical Organic Chemistry: Stereochemistry and Stereochemical Relationships, Including Conformational Inversions and Rotational Isomerization and other aspects.Name: (R)-Methyl 3-hydroxybutanoate
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