Huang, Linwei; Liu, Wei; Zhao, Liang-Liang; Zhang, Zengyu; Yan, Xiaoyu published the artcile< Base-Catalyzed H/D Exchange Reaction of Difluoromethylarenes>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is deuteriodifluoromethyl arene preparation; difluoromethylarene deuteration.
The budding deuteriodifluoromethyl group (CF2D) is a potentially significant functional group in medicinal chem. Herein, authors investigated t-BuOK-catalyzed H/D exchange reaction of difluoromethylarenes in DMSO-d6 solution The method provides excellent deuterium incorporation at the difluoromethyl group. Meanwhile, the effect of a trace amount of D2O in DMSO-d6 solution on the deuteration reaction was also investigated.
Journal of Organic Chemistry published new progress about Aralkyl fluorides Role: SPN (Synthetic Preparation), PREP (Preparation) (deuterio). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics