Chandrachud, Preeti P.; Wojtas, Lukasz; Lopchuk, Justin M. published the artcile< Decarboxylative Amination: Diazirines as Single and Double Electrophilic Nitrogen Transfer Reagents>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is decarboxylative amination redox active ester diazirine reagent.
The ubiquity of nitrogen-containing small mols. in medicine necessitates the continued search for improved methods for C-N bond formation. Electrophilic amination often requires a disparate toolkit of reagents whose selection depends on the specific structure and functionality of the substrate to be aminated. Further, many of these reagents are challenging to handle, engage in undesired side reactions, and function only within a narrow scope. Here, we report the use of diazirines as practical reagents for the decarboxylative amination of simple and complex redox-active esters. The diaziridines thus produced are readily diversifiable to amines, hydrazines, and nitrogen-containing heterocycles in one step. The reaction has also been applied in fluorous phase synthesis with a perfluorinated diazirine.
Journal of the American Chemical Society published new progress about Amination (decarboxylative). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics