Feiffers, S.; Wynberg, Hans; Strating, J. published the artcile< α-Carboxylation of esters>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is malonate monoalkyl; ester alpha carboxylation; metalation alpha ester.
Esters RR1CHCO2R2 were converted to their α-Li salts, then carboxylated to give monoesters of malonic acid. Thus, to (Me2CH)2NH in THF under N at -10 to -15° was added 2M BuLi in hexane, the mixture kept 15 min, the ester in THF added over 0.5 hr, and CO2 passed 10 min to give RR1C(CO2H)CO2R2 [R, R1 = H, Me, Et, tert-Bu, Ph, or (RR1) = cyclohexyl, cyclododecyl, 2-adamantyl; R2 = Me, Et].
Tetrahedron Letters published new progress about Carboxylation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics