Kothandaraman, Shankaran; Donnely, Karla L.; Butora, Gabor; Jiao, Richard; Pasternak, Alexander; Morriello, Gregori J.; Goble, Stephen D.; Zhou, Changyou; Mills, Sander G.; MacCoss, Malcolm; Vicario, Pasquale P.; Ayala, Julia M.; DeMartino, Julie A.; Struthers, Mary; Cascieri, Margaret A.; Yang, Lihu published the artcile< Design, synthesis, and structure-activity relationship of novel CCR2 antagonists>, Reference of 112-63-0, the main research area is tetrahydropyranylaminocyclopentanecarboxamide preparation CCR2 antagonist.
A series of novel 1-aminocyclopentyl-3-carboxamides incorporating substituted tetrahydropyran moieties have been synthesized and evaluated for their antagonistic activity against the human CCR2 receptor. Among them analog I was found to posses potent antagonistic activity.
Bioorganic & Medicinal Chemistry Letters published new progress about CC chemokine receptor CCR2 Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics