Dienel, Kasper E. G.; van Bochove, Bas; Seppala, Jukka V. published the artcile< Additive Manufacturing of Bioactive Poly(trimethylene carbonate)/β-Tricalcium Phosphate Composites for Bone Regeneration>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is additive manufacturing polytrimethylene carbonate beta tricalcium phosphate composite bone.
Implants of bioresorbable materials combined with osteoconductive calcium phosphate ceramics show promising results to replace and repair damaged bone tissue. Here we present additive manufacturing of patient-specific porous scaffolds of poly(trimethylene carbonate) (PTMC) including high amounts of β-tricalcium phosphate (β-TCP). Tensile testing of composite networks showed that addition of β-tricalcium phosphate reinforces the composites significantly. Three-dimensional structures containing up to 60 weight % β-TCP could be built by stereolithog. By lowering the content to 51 weight %, manufacturing of a large-sized patient-specific prototype was possible at high resolution Closer examination revealed that the created scaffolds contained more β-TCP on the surface of the builds. Stereolithog. therefore provides a manufacturing technique where the bioactive agent is directly available for creating an enhanced microenvironment for cell growth. The biocompatibility and bioresorption of PTMC coupled with the osteocond. of β-TCP are an important candidate to consider in additive manufacturing of bone regeneration implants.
Biomacromolecules published new progress about Biocompatibility. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
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