Leboho, Tlabo C.; van Vuuren, Sandy F.; Michael, Joseph P.; de Koning, Charles B. published the artcile< The acid-catalyzed synthesis of 7-azaindoles from 3-alkynyl-2-aminopyridines and their antimicrobial activity>, SDS of cas: 112-63-0, the main research area is azaindole derivative preparation antibacterial antifungal.
The synthesis of 7-azaindoles from 3-alkynyl-2-aminopyridines using acidic conditions, namely, a mixture of trifluoroacetic acid (TFA) and trifluoroacetic anhydride (TFAA), is described. This methodol. resulted in the synthesis of fifteen 7-azaindoles, with most containing substituents at the 2- and 5-positions. The majority of these were tested for antimicrobial activity against a range of bacteria and yeasts. The 7-azaindoles displayed the best activity against the yeasts, particularly against Cryptococcus neoformans, where activities as low as 3.9 μg ml-1 were observed
Organic & Biomolecular Chemistry published new progress about Antibacterial agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics