Bojanowski, Jan; Albrecht, Anna published the artcile< Doubly Decarboxylative Synthesis of 4-(Pyridylmethyl)chroman-2-ones and 2-(Pyridylmethyl)chroman-4-ones under Mild Reaction Conditions.>, Category: esters-buliding-blocks, the main research area is pyridylmethyl chromanone preparation; carboxy chromanone pyridyl acetic acid decarboxylative Michael addition; Michael addition; chromone-3-carboxylic acid; coumarin-3-carboxylic acid; decarboxylation.
The doubly decarboxylative Michael-type addition of pyridylacetic acid to chromone-3-carboxylic acids or coumarin-3-carboxylic acids were developed. This protocol was realized under Bronsted base catalysis, providing biol. interesting 4-(pyridylmethyl)chroman-2-ones and 2-(pyridylmethyl)chroman-4-ones in good or very good yields. The decarboxylative reaction pathway was confirmed by mechanistic studies. Moreover, an attempts to develop enantioselective variant of the cascade was described.
Molecules published new progress about C-H bond activation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics