Xu, Weici; Li, Yuanzhen; Liu, Rui; Yang, Shuang; Liu, Jian; Fang, Xinqiang published the artcile< Kinetic resolution of 2,2-disubstituted-1,3-diketones via carbene catalysis>, Application In Synthesis of 112-63-0, the main research area is formylbenzyl diketone carbene catalyst enantioselective regioselective kinetic resolution; formylalkyl diketone carbene catalyst enantioselective regioselective kinetic resolution.
The successful organocatalytic kinetic resolution of 1,3-diketones with central quaternary stereocenters through the introduction of internal nucleophiles was reported. Two basic resolution modes were established, allowing access to a broad scope of enantioenriched 1,3-diketones with quaternary stereocenters, together with a large variety of tetralone derivatives with vicinal fully substituted carbon centers, and both of them were not easily available via currently known methods. The inherent principles between the different combinations of ketone groups and the resolution patterns were also disclosed. This work constituted a good complementary choice for the construction of 1,3-diketones with quaternary stereogenic centers and provided insightful information for further studies on diketone substrate-mediated intramol. annulations and kinetic resolutions
Organic Chemistry Frontiers published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics