Taylor, D. M.; Morgan, H.; D’Silva, C. published the artcile< Characterization of chemisorbed monolayers by surface potential measurements>, Synthetic Route of 112-63-0, the main research area is chemisorption aminopropylsilane biotin avidin gold.
Chemisorption was used to immobilize uniform, low-defect d. monolayers of (3-aminopropyl)silane and of d-biotin on evaporated gold substrates. The quality of the monolayers was confirmed by surface potential measurements and by copper decoration. Avidin was immobilized to these monolayers by (i) crosslinking to the (3-aminopropyl)silane with glutaraldehyde and (ii) binding directly to the biotin ligand. The changes in surface potential observed during each immobilization step are shown to be related directly to the mol. structure of each chemisorbed layer. Significantly, when the avidin is immobilized on the biotin monolayer the tetrameric protein is oriented with one pair of biotin binding sites on the upper surface of the protein monolayer. This allows the bifunctional ligand, 1,12-bis(biotinamide)dodecane to be bound to the protein giving the possibility of attaching further protein layers to form mol. organizates suitable for mol. electronic and mol. sensing applications.
Journal of Physics D: Applied Physics published new progress about Avidins Role: PRP (Properties). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics