Saito, Seiki; Hasegawa, Takashi; Inaba, Masami; Nishida, Ryosuke; Fujii, Toshikazu; Nomizu, Seiya; Moriwake, Toshio published the artcile< Combination of borane-dimethyl sulfide complex with catalytic sodium tetrahydroborate as a selective reducing agent for α-hydroxy esters. Versatile chiral building block from (S)-(-)-malic acid>, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate, the main research area is butanoate dihydroxy preparation lactonization; borane sulfide reduction malate; borohydride dimethyl sulfide reductant; hydroxy ester selective reduction; butanolide hydroxy; butanal dihydroxy isopropylidene ketal.
BH3-Me2S complex in combination with NaBH4 is an efficient and selective reducing agent for α-hydroxy esters. Thus, reduction of di-Me (S)-(-)-malate with this agent afforded 80% (S)-HOCH2CH(OH)CH2CO2Me, which was converted into chiral building blocks I and II.
Chemistry Letters published new progress about Hydroxy esters Role: RCT (Reactant), RACT (Reactant or Reagent). 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics