Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4630-80-2, name is Methyl cyclopentanecarboxylate, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C7H12O2
The 60% sodium hydride 24.4g (0.61 muM) added to the 335 ml in tetrahydrofuran, heated to 75 C. Cyclopentyl methyl formate 50g (0.39 muM) is dissolved in acetonitrile 25g (0.61 muM), slowly adding sodium hydride to the reaction solution. The completion of the dropping, 70 C reaction 15 hours, cooling, concentrated in order to remove a portion of the solvent, adding water 180 ml, extracted with ethyl acetate three times, the organic phase is discarded. The aqueous phase is 4M hydrochloric acid to pH=2, extracted with ethyl acetate three times, drying, so as to obtain bright yellow 3 – cyclopentyl -3 – oxo third nitrile (II) 49.75g, yield is 93%
According to the analysis of related databases, 4630-80-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shanghai Bei Ka Pharmaceutical Co., Ltd.; Wang Yong; Liu Ligang; Xiang Jie; Yang Shiqiong; Li Qian; Kang Litao; (11 pag.)CN104496904; (2017); B;,
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