Shekari, Nafiseh; Vosough, Maryam; Tabar Heidar, Kourosh published the artcile< Chromatographic fingerprinting through chemometric techniques for herbal slimming pills: A way of adulterant identification>, HPLC of Formula: 112-63-0, the main research area is sibutramine amfepramone caffeine herbal slimming pill adulterant GC MS; Adulteration; Fingerprinting; GC–MS; Herbal slimming pills; MCR-ALS.
In the current study, gas chromatog.-mass spectrometry (GC-MS) fingerprinting of herbal slimming pills assisted by chemometric methods has been presented. Deconvolution of two-way chromatog. signals of nine herbal slimming pills into pure chromatog. and spectral patterns was performed. The peak clusters were resolved using multivariate curve resolution-alternating least squares (MCR-ALS) by employing appropriate constraints. It was revealed that more useful chem. information about the composition of the slimming pills can be obtained by employing sophisticated GC-MS method coupled with proper chemometric tools yielding the extended number of identified constituents. The thorough fingerprinting of the complex mixtures proved the presence of some toxic or carcinogen components, such as toluene, furfural, furfuryl alc., styrene, itaconic anhydride, citraconic anhydride, tri-Me phosphate, phenol, pyrocatechol, p-propenylanisole and pyrogallol. In addition, some samples were shown to be adulterated with undeclared ingredients, including stimulants, anorexiant and laxatives such as phenolphthalein, amfepramone, caffeine and sibutramine.
Forensic Science International published new progress about Adulterants. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics