Wang, Min; Gao, Mingzhang; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang published the artcile< [11C]GSK2126458 and [18F]GSK2126458, the first radiosynthesis of new potential PET agents for imaging of PI3K and mTOR in cancers>, Product Details of C19H34O2, the main research area is benzenesulfonamide pyridazinylquinolinylpyridinyl carbon 11 fluorine 18 labeled preparation; PET agent labeled benzenesulfonamide pyridazinylquinolinylpyridinyl preparation.
GSK2126458 is a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) with low picomolar to subnanomolar activity. [11C]GSK2126458 and [18F]GSK2126458, new potential PET agents for imaging of PI3K and mTOR in cancer, were first designed and synthesized in 40-50% and 20-30% decay corrected radiochem. yield, and 370-740 and 37-222 GBq/μmol specific activity at end of bombardment (EOB), resp.
Bioorganic & Medicinal Chemistry Letters published new progress about Positron emission tomography. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics