Raval, Saurin’s team published research in Bioorganic & Medicinal Chemistry Letters in 2008-07-15 | 112-63-0

Bioorganic & Medicinal Chemistry Letters published new progress about Structure-activity relationship. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Raval, Saurin; Raval, Preeti; Bandyopadhyay, Debdutta; Soni, Krunal; Yevale, Digambar; Jogiya, Digvijay; Modi, Honey; Joharapurkar, Amit; Gandhi, Neha; Jain, Mukul R.; Patel, Pankaj R. published the artcile< Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands>, COA of Formula: C19H34O2, the main research area is aryloxyarylaminohydroxycyclobutenedione preparation thyroid hormone receptor ligand.

Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)-phenylamino]-4-hydroxy-cyclobut-3-ene-1,2-dione I has shown selectivity towards thyroid hormone receptor β.

Bioorganic & Medicinal Chemistry Letters published new progress about Structure-activity relationship. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics