Kovacs, K.; Eros-Takacsy, T.; Ritz, I.; Hegedus-Vajda, J. published the artcile< Determination of the impurity profile of R1/CH-13584 by an online gas chromatography/mass spectrometry method>, Application of C19H34O2, the main research area is antiasthmatic CH 13584 intermediate impurity determination; gas chromatog CH 13584 intermediate impurity; mass spectrometry CH 13584 intermediate impurity.
The impurity profile of the final intermediate in the manufacture of a new, original antiasthmatic drug candidate (CH-13584) was determined by gas chromatog./mass spectrometry. Online GC/MS identification was carried out by using electron-impact ionization. Gas chromatog. separation was performed on a fused-silica column. Identification was based on mass spectral data: fragmentation patterns and elemental composition for the selected ions as well as the NIST library search for the separated impurities. GC retention times were also considered. Reference compounds with the proposed structure were synthesized and confirmed by IR, GC/MS, and NMR data. An identical impurity profile for the certified and the GMP batches proved the reliability of the synthetic process. The possibility of a potential parallel reaction of the impurities in the final reaction step was considered.
Rapid Communications in Mass Spectrometry published new progress about Mass spectra. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics