Mardenborough, Leroy G’s team published research in Bioorganic & Medicinal Chemistry in 2005-06-02 | 112-63-0

Bioorganic & Medicinal Chemistry published new progress about Antimalarials. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Mardenborough, Leroy G.; Zhu, Xue Y.; Fan, Pincheng; Jacob, Melissa R.; Khan, Shabana I.; Walker, Larry A.; Ablordeppey, Seth Y. published the artcile< Identification of bis-quindolines as new antiinfective agents>, COA of Formula: C19H34O2, the main research area is bisquindoline preparation antiinfective agent SAR.

Several N-substituted quindolines were made to further evaluate the role of N-alkylation on the activity of indoloquinolines as antifungal agents. While N-5 substitution is required for these activities, N-10 alkylation alone leads to inactive products but is tolerated in the presence of N-5 alkyl groups. It was also discovered that bis-quindolines appear to have a more expanded antimicrobial spectrum and lower cytotoxicity than their monomeric counterparts.

Bioorganic & Medicinal Chemistry published new progress about Antimalarials. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics