Murata, Ryuichi; Asano, Keisuke; Matsubara, Seijiro published the artcile< Catalytic asymmetric cycloetherification via intramolecular oxy-Michael addition of enols>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is dihydropyran preparation chemoselective enantioselective; enone bearing ketone organocatalyst asym cycloetherification oxy Michael addition.
In this study, the asym. cycloetherification of enols were presented, which were generated in situ from enone-bearing ketones, using chiral bifunctional organocatalysts bearing amino and squaramide groups. This transformation chemo- and enantioselectively afforded dihydropyran derivatives I [R1 = Ph, 4-BrC6H4, 2-naphthyl, etc.; R2 = CF3, CF2Br, CO2Et, Ph; R3 = H, C(O)Ph], which were the core structures of building blocks for synthesizing glycans.
Tetrahedron published new progress about Chemoselectivity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
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Ester – an overview | ScienceDirect Topics