Tee, Oswald S.; Paventi, Martino published the artcile< Kinetics and mechanism of the bromination of 4-pyridone and related derivatives in aqueous solution>, HPLC of Formula: 112-63-0, the main research area is bromination kinetics mechanism pyridone; tautomerism substituent effect pyridone.
The kinetics of bromination of aqueous 4-pyridone (I) and selected derivatives are determined at 25é?at pH 0.9. The tautomeric system 4-pyridone é?4-hydroxypyridine reacts with Br2 via the predominant (pyridone) tautomer at pH <6 and via the conjugate anion at pH >6. 3-Bromo-4-pyridone behaves similarly. The kinetics also reveal that the facile dibromination of I occurs because at most pH’s the monobromo derivative is actually more reactive towards Br2 by virtue of its lower pKa. From the point of view of reactivity the 4-pyridones and their anions behave as substituted phenoxide ions. 4-Methoxypyridine does not undergo bromination under comparable conditions, but rather forms a complex with Br2. Tautomerism in phenol brominations are discussed.
Canadian Journal of Chemistry published new progress about Bromination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics