Bohman, Bjorn; Flematti, Gavin R.; Unelius, C. Rikard published the artcile< Practical one-pot stereospecific preparation of vicinal and 1,3-diols>, Application In Synthesis of 73349-07-2, the main research area is diol stereoselective preparation; hydroxy ester reduction.
A facile one-pot synthesis providing vicinal diols and 1,3-diols in >95% stereoisomeric purity from com. available enantiopure hydroxy esters has been developed. The esters were reduced with DIBALH and alkylated in situ with 4-pentenylmagnesium bromide, which after workup generated the title diols as diastereomeric pairs. These pairs were easily separated by preparative chromatog., affording products with retained stereoisomeric purity from the starting materials. This method represents an expedient preparation of many common natural products, such as cerambycid beetle pheromones and intermediates towards bicyclic acetal bark beetle pheromones.
Tetrahedron Letters published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 73349-07-2 belongs to class esters-buliding-blocks, and the molecular formula is C5H10O3, Application In Synthesis of 73349-07-2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics