Kobayashi, Goro; Matsuda, Yoshiro; Natsuki, Reiko published the artcile< Quinolizine derivatives. VI. Synthesis and reaction of 1-cyano-2-methylthio-4H-quinolizin-4-ones>, Synthetic Route of 30095-98-8, the main research area is quinolizinone methylthio; methylthioquinolizinone; cyanomethylthioquinolizinone.
Reaction of æµ?æµ?-bis(methylthio)methylene-2-pyridylacetonitrile (I) and active methylene compounds R2CH2CO2R1 (II) (R1 = Me, Et; R2 = CN, CO2Me, 2-O2NC6H4, etc.) in Me2SO, in the presence of K2CO3, afforded 1-cyano-2-methylthio-4H-quinolizin-4-ones (III) with the corresponding substituent in 3-position. Reaction of some of these 3-substituted compounds with benzylamine produced 2-benzylamino-1-cyano-4H-quinolizin-4-ones. Reduction of 3(2-pyridyl) derivative of III over Raney Ni gave 1-cyano-3-(2-pyridyl)-4H-quinolizin-4-one.
Chemical & Pharmaceutical Bulletin published new progress about Cycloaddition reaction. 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Synthetic Route of 30095-98-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics