Dai, Yubei; Wang, Fang; Zhu, Shengqing; Chu, Lingling published an article in 2022. The article was titled 《Selective Ni-catalyzed cross-electrophile coupling of alkynes, fluoroalkyl halides and vinyl halides》, and you may find the article in Chinese Chemical Letters.Safety of Diethyl 2-methylmalonate The information in the text is summarized as follows:
A Ni-catalyzed three-component cross-electrophile coupling of alkynes with alkenyl halides and fluoroalkyl halides to generate fluoroalkyl-incorporated 1,3-dienes was reported. This mild and operationally simple protocol was distinguished by its broad substrate scope and excellent chemo-, regio- and stereoselectivity, offering a new and organometallic agent-free platform for the construction of fluoroalkyl-incorporated diene motifs. Preliminary mechanistic studies were conducted to probe the potential reaction pathway. In the part of experimental materials, we found many familiar compounds, such as Diethyl 2-methylmalonate(cas: 609-08-5Safety of Diethyl 2-methylmalonate)
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Safety of Diethyl 2-methylmalonate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics