Straub, Matthew R.; Birman, Vladimir B. published an article in 2021. The article was titled 《Organocatalytic Kinetic Resolution of N-Boc-Isoxazolidine-5-ones》, and you may find the article in Organic Letters.Reference of N-tert-Butoxycarbonylhydroxylamine The information in the text is summarized as follows:
An effective activation of racemic N-Boc-isoxazolidine-5-ones toward enantioselective alcoholysis by bifunctional organocatalysts was demonstrated. In fact,some of the selectivity factors recorded in this study were among the highest ever obtained in this type of transformation, thus highlighted the potential of these underexplored acyl donors in asym. catalysis. From a practical standpoint, the new methodol. was expected to offer a mechanistically different alternative to existing asym. approaches to isoxazolidinones I [R1 = i-Pr, Ph, 2-thienyl, etc.; R2 = t-Bu, Bn] and could be used to upgrade their level of enantiomericenrichment.N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3Reference of N-tert-Butoxycarbonylhydroxylamine) was used in this study.
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Reference of N-tert-Butoxycarbonylhydroxylamine
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics