Yu, Tongyan’s team published research in Organic Chemistry Frontiers in 2021 | CAS: 924-99-2

Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Recommanded Product: 924-99-2

In 2021,Organic Chemistry Frontiers included an article by Yu, Tongyan; Ji, Fei; Huang, Daichuan; Gao, Ya; Shi, Zhaoping; Sha, Xuan; Xu, Jiangyan; You, Siliang; Zhang, Mingzhi; Sha, Qiang. Recommanded Product: 924-99-2. The article was titled 《Facile synthesis of penta-substituted pyrroles and pyrrole-fused piperidin-4-ones via four component reactions of 2,3-diketoesters, anilines and enaminones》. The information in the text is summarized as follows:

Herein, a novel BF3.Et2O mediated four component reaction of 2,3-diketoesters RC(O)C((OH)2)C(O)R1 (R = Me, 2-phenylethenyl, naphthalen-2-yl, thiophen-2-yl, etc.; R1 = OMe, OEt, (2-methylpropyl)oxidanyl, dimethylaminyl, OBn), anilines 4-R2C6H4NH2 (R2 = H, Me, Br, methoxycarbonyl, etc.) and enaminones R3C(O)CH=CHN(CH3)2 (R3 = OEt, Ph, furan-2-yl, etc.)/R4CH=CHC(O)CH=CHN(CH3)2 (R4 = Ph, 4-methoxyphenyl), providing highly functionalized pyrroles I and pyrrole-fused piperidin-4-ones II in moderate to good yields was presented. The key to success lies in the utilization of enaminone as the substrate and precise capture of the carbocation intermediate by anilines, allowing the amination to occur at the 5-position smoothly. This strategy is potentially applicable to diverse nucleophilic reagents. Moreover, an intramol. version of this strategy can be utilized to form fused heterocycles.Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2Recommanded Product: 924-99-2) was used in this study.

Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Recommanded Product: 924-99-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics