Quality Control of Ethyl oxalyl monochlorideIn 2020 ,《Transition-metal free direct C-H functionalization of quinoxalin-2(1H)-ones with oxamic acids leading to 3-carbamoyl quinoxalin-2(1H)-ones》 appeared in Organic Chemistry Frontiers. The author of the article were Yuan, Jin-Wei; Zhu, Jun-Liang; Zhu, Hu-Lin; Peng, Fang; Yang, Liang-Yu; Mao, Pu; Zhang, Shou-Ren; Li, Yan-Chun; Qu, Ling-Bo. The article conveys some information:
A practical transition-metal free decarboxylative coupling reaction of oxamic acids with quinoxalin-2(1H)-ones was developed under mild conditions. This transformation provided an efficient approach for the preparation of 3-carbamoyl quinoxalin-2(1H)-ones, which are important subunits in biol. active natural products and medicinal chem. This protocol features broad substrate scope, good yields and mild reaction conditions. In the experiment, the researchers used Ethyl oxalyl monochloride(cas: 4755-77-5Quality Control of Ethyl oxalyl monochloride)
Ethyl oxalyl monochloride(cas: 4755-77-5) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Quality Control of Ethyl oxalyl monochloride
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics