Power, David P.; Lozach, Olivier; Meijer, Laurent; Grayson, David H.; Connon, Stephen J. published the artcile< Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones>, Related Products of 112-63-0, the main research area is azapaullones preparation CDK GSK inhibitor.
A remarkably concise, chromatog.-free route to the parent compound of the paullone family of cyclin-dependent kinase (CDK) inhibitors is reported. A similar strategy allowed the synthesis of the hitherto missing 9-azapaullone and its protonated, N-oxidized and N-alkylated derivatives Screening studies identified an active and strongly selective inhibitor of CDK9/cyclin T.
Bioorganic & Medicinal Chemistry Letters published new progress about Enzyme inhibitors. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics