Farid, Umar; Aiello, Maria Luisa; Connon, Stephen J. published the artcile< Highly Enantioselective Catalytic Kinetic Resolution of α-Branched Aldehydes through Formal Cycloaddition with Homophthalic Anhydrides>, Electric Literature of 112-63-0, the main research area is dihydroisocoumarin diastereoselective preparation; homophthalic anhydride aldehyde cycloaddition squaramide substituted catalyst; branched alc enantioselective preparation; chiral aldehyde enantioselective preparation reduction; aldehyde enantioselective catalytic kinetic resolution; cycloaddition reaction; dynamic kinetic resolution; enolizable anhydrides; lactones; organocatalysis.
A new catalytic methodol. was developed to promote an efficient one-pot kinetic resolution of racemic aldehydes ArCHRCHO [R = Me, Et, allyl; Ar = Ph, 1-naphthyl, 2-thienyl, etc.] with selectivity of up to 91 (99:1 d.r., >99 % ee) in a cycloaddition with enolizable anhydrides to afford dihydroisocoumarins I (a core prevalent in natural products and mols. of medicinal interest) containing three contiguous stereocenters.
Chemistry – A European Journal published new progress about Alcohols, chiral Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics