Galaverna, Gianni; Panto, Francesco; Dossena, Arnaldo; Marchelli, Rosangela; Bigi, Franca published the artcile< Chiral separation of unmodified α-hydroxy acids by ligand exchange HPLC using chiral copper(II) complexes of (S)-phenylalaninamide as additives to the eluent>, Computed Properties of 112-63-0, the main research area is phenylalaninamide copper hydroxy acid liquid chromatog; hydroxy acid chiral separation HPLC copper.
Copper(II) complexes of (S)-phenylalaninamide have been successfully used for the direct enantiomeric separation of unmodified (R,S)-α-hydroxy acids in reversed phase HPLC. The effect of various parameters (pH, eluent polarity, selector concentration) on enantioselectivity is discussed. Evidence is provided that a mechanism of ligand exchange is actually occurring during the chromatog. separation The method is very convenient and easy to use, and the chiral selector is com. available and can be recovered at the end of the anal. A conventional achiral RP-ODS-2 column is used and no pretreatment of the samples is required. This method allows the accurate determination of the enantiomeric excess of α-hydroxy acids in synthetic and biol. samples.
Chirality published new progress about Hydroxycarboxylic acids Role: ANT (Analyte), ANST (Analytical Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics