Hopkins, Brett Andrew; Zavesky, Blane; White, Derick published the artcile< Thioetherification of Aryl Halides with Thioacetates>, Application of C19H34O2, the main research area is thioarene preparation; thioacetate aryl halide thioetherification palladium catalyst.
A palladium-catalyzed cross-coupling of thioacetates RSC(O)CH3 (R = t-Bu, Ph, furan-2-ylmethyl, 4-methylcyclohexyl, etc.) and aryl halides R1Br (R1 = Ph, isoquinolin-8-yl, 4-phenylphenyl, cyclohex-1-en-1-yl, etc.) is described herein. Using a catalyst screening kit, tBuBrettPhos Pd G3 was found to be a unique catalyst for this reaction, affording the desired thioarene products RSR1 in high yields under mild reaction conditions. The thioacetate starting materials are readily available, allowing for quick access to these more lab friendly reagents. Reactions described herein range from the late-stage coupling of complex thioacetates to the first report of a mild set of conditions for thiomethylation of aryl halides.
Journal of Organic Chemistry published new progress about Acetates Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics