Adam, Waldemar; Fell, Rainer T.; Hoch, Ute; Saha-Moeller, Chantu R.; Schreier, Peter published the artcile< Kinetic resolution of chiral α-hydroperoxy esters by horseradish peroxidase-catalyzed enantioselective reduction to α-hydroxy esters>, COA of Formula: C5H10O3, the main research area is kinetic resolution chiral hydroperoxy ester; horseradish peroxidase catalyzed enantioselective reduction; hydroxy ester.
The kinetic resolution of the Me α-hydroperoxy esters 4 has been investigated by horseradish peroxidase (HRP)-catalyzed reduction to the corresponding optically active α-hydroxy esters 5 in the presence of guaiacol. The method allows for the first time the preparation of enantiomerically pure (ee > 97%) Me (R)-2-hydroperoxybutyrate (4a). The HRP enzyme is sensitive to the steric demand of the ester alkyl side chain, as manifested by Et (ee > 97%) and iso-Pr (ee 79%), while the tert-Bu derivative is not accepted by the enzyme (no reduction).
Tetrahedron: Asymmetry published new progress about Chiral recognition. 73349-07-2 belongs to class esters-buliding-blocks, and the molecular formula is C5H10O3, COA of Formula: C5H10O3.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics