Dede, Fabiana; Piccolo, Oreste; Vigo, Daniele published the artcile< Dimethyl Fumarate: Heterogeneous Catalysis for the Development of an Innovative Flow Synthesis>, Synthetic Route of 112-63-0, the main research area is dimethyl fumarate catalysis development innovative synthesis.
The present work describes the development of an improved synthesis of the active pharmaceutical ingredient (API) di-Me fumarate. The use of continuous flow technol. and the newly developed methylation conditions solve some of the issues of previous com. production strategies, e.g., reaching complete conversion and avoiding the formation of toxic impurities. The optimization was carried out using the design of experiment approach and afforded a very efficient, sustainable process, suitable for the industrial application.
Organic Process Research & Development published new progress about Experimental design. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics