Zhang, Dehui; Zheng, Hongchao; Wang, Xiaodong published the artcile< General and cost-effective synthesis of 1-heteroaryl/arylcycloalkylamines and their broad applications>, SDS of cas: 112-63-0, the main research area is heteroaryl aryl cycloalkylamine preparation.
A general and cost-effective route has been developed to synthesize 1-heteroaryl-substituted cycloalkylamines from readily available heteroarylacetate in good yields. This synthesis features a LHMDS promoted cyclization and one-pot hydrolysis/Curtius rearrangement. This route can be easily carried out on multi-gram scale and be also used to prepare 1-aryl-substituted cycloalkyl/cycloheteroalkylamines. 1-Heteroaryl/aryl-substituted cycloalkyl/cycloheteroalkylamines are versatile building blocks and their applications in organic and medicinal chem. have been demonstrated in the synthesis of morpholine and N-methylpiperazine analogs and a known Rho kinase inhibitor compound
Tetrahedron published new progress about Alicyclic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics