Safety of 3-(Methoxycarbonyl)benzoic acidOn March 14, 2019, Joshi, Sumedh; Fedoseyenko, Dmytro; Mahanta, Nilkamal; Ducati, Rodrigo G.; Feng, Mu; Schramm, Vern L.; Begley, Tadhg P. published an article in ACS Medicinal Chemistry Letters. The article was 《Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis》. The article mentions the following:
Aminofutalosine synthase (MqnE) catalyzes an important rearrangement reaction in menaquinone biosynthesis by the futalosine pathway. We report the identification of previously unreported inhibitors of MqnE using a mechanism-guided approach. The best inhibitor shows efficient inhibitory activity against Helicobacter pylori (IC50 = 1.8 ± 0.4 μM) and identifies MqnE as a promising target for antibiotic development. After reading the article, we found that the author used 3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0Safety of 3-(Methoxycarbonyl)benzoic acid)
3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Safety of 3-(Methoxycarbonyl)benzoic acid Polyesters are important plastics, with monomers linked by ester moieties.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics