Li, Quan-Zhe; Lian, Peng-Fei; Tan, Fu-Xin; Zhu, Guo-Dong; Chen, Chao; Hao, Yu; Jiang, Wei; Wang, Xun-Hui; Zhou, Jia; Zhang, Shu-Yu published the artcile< Organocatalytic Enantioselective Construction of Heterocycle-Substituted Styrenes with Chiral Atropisomerism>, Electric Literature of 112-63-0, the main research area is heterocycle substituted phenylvinylnaphthaleneamine enantioselective preparation; indole arylaminoalkynylnaphthalene enantioselective addition organocatalyst; hydroxycoumarin arylaminoalkynylnaphthalene enantioselective addition organocatalyst.
We have developed a novel π-π interaction and dual H-bond concerted control strategy to construct axially chiral naphthylamine heterocycles. With ortho-alkynyl-naphthylamines as the electrophile, indoles and 4-hydroxycoumarins were efficiently employed to construct axially chiral skeletons in good yields and with excellent enantioselectivities (up to 97% enantiomeric excess). Furthermore, the resulting products could be converted to potential squaramides featuring organic catalysts.
Organic Letters published new progress about 4-Hydroxycoumarins Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics