《A simple route towards the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles from primary amines and 1,3-dicarbonyl compounds under metal-free conditions》 was published in Organic & Biomolecular Chemistry in 2019. These research results belong to Guo, Ningxin; Liu, Xiufen; Xu, Hongyan; Zhou, Xi; Zhao, Huaiqing. Synthetic Route of C6H10O3 The article mentions the following:
An acetic acid-promoted approach that enabled the synthesis of 1,4,5-trisubstituted 1,2,3-triazole derivatives were achieved. This transformation employed readily available primary amines, 1,3-dicarbonyls and tosyl azide as the starting materials via a cycloaddition reaction under metal-free conditions. The reaction provideed a simple access to fully substituted 1,2,3-triazoles from com. substrates in moderate to excellent yields. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-oxovalerate(cas: 30414-53-0Synthetic Route of C6H10O3)
Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Synthetic Route of C6H10O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics