Prathap, K. Jagadeesh; Himaja, M.; Mali, Sunil V. published the artcile< 5-Amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxylamino acids as potent insecticidal agents>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is chlorohydrazinopyridine cyclocondensation ethoxymethylene cyanoacetate; pyridyl aminopyrazole acid preparation coupling amino acid ester; amino chloropyridinyl pyrazole carboxylamino acid preparation insecticidal antibacterial activity.
A new series of 5-amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxy amino acid derivatives were synthesized by using benzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (BOP) as coupling reagent. The key intermediate 5-amino-1-(5-chloropyridin-2-yl)-1H-pyrazole-4-carboxylic acid was synthesized by condensation of 5-chloro-2-hydrazinopyridine with Et (ethoxymethylene)cyanoacetate followed by basic hydrolysis. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR and Mass spectral anal. and were evaluated for their antimicrobial and insecticidal activities. Some of the synthesized compounds showed potent insecticidal activity and moderate antibacterial activity with respect to the standard drug.
Indian Journal of Heterocyclic Chemistry published new progress about Amino acid esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics