SDS of cas: 924-99-2On October 12, 2021 ,《Synthesis of quinolone antibiotic analogues: a multistep synthetic chemistry experiment for undergraduates》 was published in Journal of Chemical Education. The article was written by Bailie, Alexandra E.; Nortcliffe, Andrew. The article contains the following contents:
A multistep synthesis of quinolone antibiotic analogs was developed as a laboratory experiment for intermediate/advanced undergraduate students. Students can synthesize a range of desfluoroenoxacin analogs via a five-step sequence. The experiment includes a range of key practical laboratory techniques including thin-layer chromatog. (TLC), liquid-liquid extraction, trituration, recrystallization and the characterization of compounds by IR and NMR spectroscopy. The experiment provides an opportunity for students to carry out fundamental organic chem. transformations from the curriculum such as the preparation of acyl chlorides, 1,4-conjugate addition-elimination, heterocycle synthesis, nucleophilic aromatic substitution and ester hydrolysis. The five-step sequence does not require column chromatog. and can be adapted to a range of laboratory settings. In the experiment, the researchers used Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2SDS of cas: 924-99-2)
Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.SDS of cas: 924-99-2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics