《A General and Practical Synthesis of Chiral 1,2-Oxazetidines》 was published in Asian Journal of Organic Chemistry in 2020. These research results belong to Yang, Jinggang; Wu, Binyu; Hu, Lin. COA of Formula: C5H11NO3 The article mentions the following:
Herein, a general and practical method to access a series of structurally diverse chiral 1,2-oxazetidines I [R = R1 = H, i-Pr, Ph, etc.; RR1 = (CH2)4; stereo = R, S] from readily available chiral epoxides and α-bromo esters in 3-4 steps by using mild Mitsunobu reactions as an efficient ring-closure approach to form the highly strained four-membered rings was reported. The new method was operationally simple, and a range of N-nosyl-protected 3- and 4-substituted as well as 3,4-disubstituted chiral 1,2-oxazetidines could be conveniently prepared in gram-scale with excellent enantioselectivities (93-99% ee) and good overall yields for the first time. In the experiment, the researchers used N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3COA of Formula: C5H11NO3)
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).COA of Formula: C5H11NO3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics