Yang, Ke; Ma, Zhiyan; Tong, Hong-Xiao; Sun, Xiao-Qiang; Hu, Xiao-Yu; Li, Zheng-Yi published the artcile< Asymmetric Michael addition reactions catalyzed by a novel upper-rim functionalized calix[4]squaramide organocatalyst>, Related Products of 112-63-0, the main research area is chromenone preparation enantioselective; unsaturated carbonyl dicarbonyl Michael calixsquaramide organocatalyst; nitroalkane preparation enantioselective; aryl nitroolefin acetylacetone Michael calixsquaramide organocatalyst.
A novel upper-rim functionalized calix[4]squaramide organocatalyst bearing bis-squaramide and cyclohexanediamine scaffolds was designed and prepared to catalyze a serial of asym. Michael addition of 1,3-dicarbonyl compounds to α,β-unsaturated carbonyl compounds to afford chromenones, e.g., I in high yields (up to 99%) and good to excellent enantiomeric excesses (up to 99% ee). This method was also used for the synthesis of nitroalkanes II [R1 = Ph, 4-MeC6H4, 4-ClC6H4, etc.] via reaction of aryl nitroolefins with acetylacetone. The comparative experiments indicated that the cooperative effect between calixarenes cavitives and chiral catalytic centers on this calix[4]squaramide catalyst could promote these reactions.
Chinese Chemical Letters published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Related Products of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics