Thomas, Eric J.; Williams, Andrew C. published the artcile< Development of a synthesis of lankacidins: stereoselective synthesis of the δ-lactone fragment>, Product Details of C6H10O5, the main research area is lankacidin delta lactone stereoselective preparation.
Electrophiles react at C(3) stereoselectivity on the less hindered face of the enolate derived from the 4-substituted azetidinone I to give products in which the new substituent is trans to the (tert-butyldimethylsilyloxymethyl) group at C(4). Aldol addition with 3-(tert-butyldimethylsilyloxy)propanal gave the alcs. II and III, ratio 80:20, which were separated as mixtures of C(1′). Oxidation, followed by exchange of protecting groups, gave the 3-(1′-oxopropyl)azetidinones which, on selective monodesilylation, were converged into the δ-lactones IV and V. The stereochem. of the major δ-lactone IV corresponds to that of the lankacidins at C(2) and C(3).
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry published new progress about 617-55-0. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Product Details of C6H10O5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics