Sun, Qingrong; Wang, Xingyi; Xu, Yinan; Yang, Weiqing; Ma, Menglin published their research in Indian Journal of Heterocyclic Chemistry in 2021. The article was titled 《One-step synthesis of 3-unsubstituted 4-hydroxy-2(1H)-quinoline》.Electric Literature of C8H14O4 The article contains the following contents:
3-Unsubstituted 4-hydroxy-2(1H)-quinolone (DHQ) derivatives were synthesized from aniline derivatives and di-Et malonate at low temperature using AlCl3 as catalyst and Eaton reagent as acidic environment. A reaction mechanism was proposed and elucidated. Different synthetic intermediates were specially prepared or purified and used to understand the reaction and validation mechanism.Diethyl 2-methylmalonate(cas: 609-08-5Electric Literature of C8H14O4) was used in this study.
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Electric Literature of C8H14O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics