In 2022,Ochiai, Hidenori; Hayashi, Wakana; Nishiyama, Akira; Fujita, Ryunosuke; Kubota, Shunichi; Sasagawa, Miwa; Nishi, Tatsuya published an article in Organic Process Research & Development. The title of the article was 《Asymmetric Synthesis of Optically Active 3-Cyclohexene-1-carboxylic Acid utilizing Lactic Ester as a Chiral Auxiliary in Diastereoselective Diels-Alder Reaction》.HPLC of Formula: 4248-19-5 The author mentioned the following in the article:
The optically active (S)/(R)-3-cyclohexene-1-carboxylic acid was synthesized through a TiCl4-catalyzed diastereoselective Diels-Alder reaction utilizing lactic ester like 2-propenoic acid, (1R)-2-ethoxy-1-methyl-2-oxoethyl ester as a chiral auxiliary which can be removed by washing with H2O. The (S)- and (R)-isomers were both derived from easily available Et L-lactate. In the part of experimental materials, we found many familiar compounds, such as tert-Butyl carbamate(cas: 4248-19-5HPLC of Formula: 4248-19-5)
tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.HPLC of Formula: 4248-19-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics