Remuinan, M. J.; Pattenden, G. published the artcile< Total synthesis of (-)-pateamine, a novel polyene bis-macrolide with immunosuppressive activity from the sponge Mycale sp.>, Electric Literature of 617-55-0, the main research area is pateamine total synthesis.
A concise and convergent synthesis of the polyene thiazole-containing 19-membered bis-lactone (-)-pateamine is described. The synthesis features both the intra- and intermol. Stille sp2-sp2 coupling reactions to elaborate the E,Z-diene macrolide core and the side-chain all-E polyene portion of the natural product, and highlights the scope for enantiopure sulfinimine intermediates in the synthesis of chiral β-amino ester moieties in complex structures.
Tetrahedron Letters published new progress about Stille coupling reaction. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Electric Literature of 617-55-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics