Lamhauge, Johannes N.; Corti, Vasco; Liu, Yidong; Joergensen, Karl Anker published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Enantioselective α-Etherification of Branched Aldehydes via an Oxidative Umpolung Strategy》.HPLC of Formula: 36016-38-3 The article contains the following contents:
A survey of benzoquinone oxidants identified p-fluoranil and DDQ as suitable reaction partners. p-Fluoranil enables the preparation of α-aryloxylated aldehydes using phenol nucleophiles in up to 91% ee, following either a one-step or a two-step, one-pot protocol. DDQ allowed for a more general etherification protocol in combination with a broader range of alc. nucleophiles with enantioselectivities up to 95% ee. Control experiments and isolation of a key quinol intermediate supports a mechanism proceeding via an SN2 dynamic-kinetic resolution These studies provided the basis for an aminocatalytic umpolung concept that allows for the asym. construction of tertiary ethers in the α-position of aldehydes. In the experiment, the researchers used many compounds, for example, N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3HPLC of Formula: 36016-38-3)
N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.HPLC of Formula: 36016-38-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics