Strazzolini, Paolo; Verardo, Giancarlo; Gorassini, Fausto; Giumanini, Angelo G. published the artcile< Orientation effect of side chain substituents in aromatic substitution. Induced ortho nitration>, Application In Synthesis of 30095-98-8, the main research area is ortho nitration toluene derivative regiochem; benzeneacetic acid ortho nitration.
The presence of a free carboxyl or ester function on the α-carbon of toluene induces the nitration of the Ph ring in the ortho position at or above the statistical value (chaperon effect), when pure HNO3 is used in CH2Cl2 solution This is at variance with the results of classical nitration in H2SO4, where p-nitration predominates by far and m-nitration occurs to a remarkable extent. The new finding is explained in terms of precomplex formation.
Bulletin of the Chemical Society of Japan published new progress about Nitration. 30095-98-8 belongs to class esters-buliding-blocks, and the molecular formula is C9H9NO4, Application In Synthesis of 30095-98-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics